Increased skeletal muscle amino acid release with light exercise in deconditioned patients with heart failure.

نویسندگان

  • Roberto Aquilani
  • Cristina Opasich
  • Maurizia Dossena
  • Paolo Iadarola
  • Alessandra Gualco
  • Patrizia Arcidiaco
  • Simona Viglio
  • Federica Boschi
  • Manuela Verri
  • Evasio Pasini
چکیده

Cardiol 1999;83:477–81. 4. Misra A, Vikram NK. Clinical and pathophysiological consequences of abdominal adiposity and abdominal adipose tissue depots. Nutrition 2003;19:457–66. 5. Rea TD, Heckbert SR, Kaplan RC, et al. Body mass index and the risk of recurrent coronary events following acute myocardial infarction. Am J Cardiol 2001;88:467–72. 6. Wilson PW, D’Agostino RB, Sullivan L, et al. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med 2002;162:1867–72. 7. Powell BD, Lennon RJ, Lerman A, et al. Association of body mass index with outcome after percutaneous coronary intervention. Am J Cardiol 2003;91:472–6. 8. Potapov EV, Loebe M, Anker S, et al. Impact of body mass index on outcome in patients after coronary artery bypass grafting with and without valve surgery. Eur Heart J 2003;24:1933–41. 9. Wolk R, Berger P, Lennon RJ, et al. Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease. Circulation 2003;108:2206–11. 10. Hoit BD, Gilpin EA, Maisel AA, et al. Influence of obesity on morbidity and mortality after acute myocardial infarction. Am Heart J 1987;114:1334–41. 11. Horwich TB, Fonarow GC, Hamilton MA, et al. The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol 2001;38:789–95. 12. Davos CH, Doehner W, Rauchhaus M, et al. Body mass and survival in patients with chronic heart failure without cachexia: the importance of obesity. J Card Fail 2003;9:29–35. 13. Anker S, Ponikowski P, Varney S, et al. Wasting as independent risk factor for mortality in chronic heart failure. Lancet 1997;349: 1050 –3. 14. Anker SD, Negassa A, Coats AJ, et al. Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting enzyme inhibitors: an observational study. Lancet 2003;361:1077–83.

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عنوان ژورنال:
  • Journal of the American College of Cardiology

دوره 45 1  شماره 

صفحات  -

تاریخ انتشار 2005